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10.1016/j.coph.2019.08.001 Curr

Phase III detoxification involves the transport and elimination of these conjugated toxins out of hepatocytes, primarily into the bile or urine for excretion, ensuring their removal from the body

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Its various mechanisms, including its antioxidant effects, the stimulation of pheomelanin synthesis instead of eumelanin, and interference with intracellular trafficking of melanogenic enzymes, contribute to its antimelanogenic properties

IKKbeta mediates homeostatic function in inflammation via competitively phosphorylating AMPK and IkappaBalpha

Once sarin binds to cholinesterase the chemical stability of it's interaction with the enzyme can become irreversible with time due to the loss of an alkyl group